115765-07-6Relevant articles and documents
Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines
Aziz, Marian W.,Kamal, Aliaa M.,Mohamed, Khaled O.,Elgendy, Adel A.
, (2021/05/10)
New acetamide (IV a-e) and 1,3-thiazolidinone derivatives (VII a-e) were designed, synthesized and assessed for their cytotoxic activity against MCF-7 and A549 cell lines along with their lead compounds (erlotinib and gefitinib). The newly designed compou
SYNTHESIS OF SOME 3-SUBSTITUTED 4(3H)-QUINAZOLINONE AND 4(3H)-QUINAZOLINETHIONE DERIVATIVES AND RELATED FUSED BIHETEROCYCLIC RING SYSTEMS
Abdel-Megeed, Mohamed Farghali,Teniou, Abderrahman
, p. 329 - 335 (2007/10/02)
The reactions of 2-phenyl-4(3H)-quinazolinone, 2-phenyl-3-amino-4(3H)-quinazolinone, and corresponding thiones with phenyl isocyanate or phenyl isothiocyanate were investigated.The resulting urea and thiourea quinazoline or quinazolinethione derivatives r