116026-78-9

Basic information

• Product Name: 2-<4-(2-bromoethoxy)benzyl>-1-cyclohexanone
• Synonyms: 2-<4-(2-bromoethoxy)benzyl>-1-cyclohexanone
• CAS NO: 116026-78-9
• Molecular Weight: 311.219
• Mol File: 116026-78-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-<4-(2-bromoethoxy)benzyl>-1-cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-<4-(2-bromoethoxy)benzyl>-1-cyclohexanone(116026-78-9)
• EPA Substance Registry System: 2-<4-(2-bromoethoxy)benzyl>-1-cyclohexanone(116026-78-9)

Safety Data

• Hazardous Substances Data: 116026-78-9(Hazardous Substances Data)

Usage

Chemical compound

2-<4-(2-bromoethoxy)benzyl>-1-cyclohexanone

Type

Cyclohexanone derivative

Functional groups

Benzyl group with a bromoethoxy substituent

Uses

Organic synthesis, medicinal chemistry, production of pharmaceuticals and bioactive compounds, manufacturing of fragrances, flavorings, fine chemicals

Valuable for

Research and development in organic chemistry due to the presence of bromoethoxy and benzyl groups

Upstream product

• 108-94-1 cyclohexanone 
• 37722-64-8 2-(4-methoxybenzyl)cyclohexan-1-one 
• 1125-99-1 1-(1-Cyclohexen-1-yl)pyrrolidine 
• 22081-10-3 2-(4-Hydroxybenzyl)-1-cyclohexanone 
• 106-93-4 ethylene dibromide 

Downstream Products

• 116126-38-6 Pyridine-2-carbaldehyde O-{2-[4-((1R,2S)-2-hydroxy-cyclohexylmethyl)-phenoxy]-ethyl}-oxime 
• 116026-85-8 Pyridine-2-carbaldehyde O-{2-[4-((1R,2R)-2-hydroxy-cyclohexylmethyl)-phenoxy]-ethyl}-oxime 
• 116126-40-0 Propionaldehyde O-{2-[4-((1R,2S)-2-hydroxy-cyclohexylmethyl)-phenoxy]-ethyl}-oxime 
• 116026-82-5 Propionaldehyde O-{2-[4-((1R,2S)-2-hydroxy-cyclohexylmethyl)-phenoxy]-ethyl}-oxime 
• 116126-39-7 Propionaldehyde O-{2-[4-((1R,2R)-2-hydroxy-cyclohexylmethyl)-phenoxy]-ethyl}-oxime 
• 116127-04-9 Propionaldehyde O-{2-[4-((1R,2R)-2-hydroxy-cyclohexylmethyl)-phenoxy]-ethyl}-oxime 
• 155854-10-7 {2-[4-(2-Oxo-cyclohexylmethyl)-phenoxy]-ethyl}-carbamic acid prop-2-ynyl ester 
• 155854-02-7 {2-[4-(2-Oxo-cyclohexylmethyl)-phenoxy]-ethyl}-carbamic acid propyl ester 
• 155854-06-1 {2-[4-(2-Oxo-cyclohexylmethyl)-phenoxy]-ethyl}-carbamic acid isopropyl ester 
• 155853-98-8 {2-[4-(2-Oxo-cyclohexylmethyl)-phenoxy]-ethyl}-carbamic acid methyl ester 
• 103724-87-4 trans-2-ethyl N-<2-<4-(2-hydroxy-1-cyclohexylmethyl)phenoxy>ethyl>carbamate 
• 103724-87-4 cis-2-ethyl N-<2-<4-(2-hydroxy-1-cyclohexylmethyl)phenoxy>ethyl>carbamate 

Relevant articles and documents

Synthesis and structure-activity relationships of juvenoids derived from 2-(4-hydroxybenzyl)cycloalkan-1-ones

Juvenoids 16-30, 32, 36, 38-41, 44-46, and 49-56 containing carbamate, carbonate, and urea moieties in the molecule were synthesized and subjected to a biological screening. Carbamate juvenoids 1-4 were used as reference compounds for a detailed structure-activity study of their analogues. A clear relationship between the nature of the side chain functional group and the biological activity was found. Surprisingly, not only the juvenoids 1,4 but also 38-41, the compounds with a reversed carbamate N,O-substitution pattern, showed very promising biological activity. In contrast, the carbonate and urea derivatives displayed a remarkably low activity. The relationship between the size and substitution at atoms C(2) and C(3) of the saturated ring and the biological activity is very complex and is still not completely understood.

Oxime Ethers as Potential Juvenoids

The oxime ethers 7a-14a and 7b-10b were synthesized in order to study their potential insecticidal properties.The respective syn- (7a-10a) and anti-isomers (7b-10b) of the oxime ethers were separated.Only syn-isomer formation was observed during the synth