116141-70-9

Basic information

• Product Name: (+)-Menthyl 4-ethoxy-2-oxo-3-butenoate
• CAS NO: 116141-70-9
• Molecular Weight: 282.38
• Mol File: 116141-70-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+)-Menthyl 4-ethoxy-2-oxo-3-butenoate(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-Menthyl 4-ethoxy-2-oxo-3-butenoate(116141-70-9)
• EPA Substance Registry System: (+)-Menthyl 4-ethoxy-2-oxo-3-butenoate(116141-70-9)

Safety Data

• Hazardous Substances Data: 116141-70-9(Hazardous Substances Data)

Upstream product

• 81529-62-6 (+)-Menthyl chlorooxoacetate 
• 109-92-2 ethyl vinyl ether 
• 15356-60-2 (1S,2R,5S)-(+)-menthol 

Relevant articles and documents

Highly Efficient Syntheses of Alkyl 3,3-Dialkoxypropanoates, Alkyl 4-Ethoxy-2-oxo-3-butenoates, and Monoprotected Malonaldehydes

Haloform reaction of 4-alkoxy-1,1,1-trichloro-3-buten-2-ones, which can be obtained by acylation of enol ethers, gives 3,3-dialkoxypropanoic esters.Transacetalization of ethyl 3,3-diethoxypropanoate with 2,2-dimethyl-1,3-propanediol, followed by reduction and oxidation with DMSO/oxalyl chloride yields a monoprotected malonaldehyde. 4-Ethoxy-2-oxo-3-butenoates are synthesized either by acylation of enol ethers with alkoxalyl chlorides or by Claisen condensation of alkyl pyruvates with orthoesters.