1163708-04-0Relevant articles and documents
Discovery of thioether-bridged cyclic pentapeptides binding to Grb2-SH2 domain with high affinity
Jiang, Sheng,Liao, Chenzhong,Bindu, Lakshman,Yin, Biaolin,Worthy, Karen W.,Fisher, Robert J.,Burke Jr., Terrence R.,Nicklaus, Marc C.,Roller, Peter P.
supporting information; experimental part, p. 2693 - 2698 (2010/03/03)
Blocking the interaction between phosphotyrosine (pTyr)-containing activated receptors and the Src homology 2 (SH2) domain of the growth factor receptor-bound protein 2 (Grb 2) is considered to be an effective and non-cytotoxic strategy to develop new ant