1165869-58-8

Basic information

• Product Name: C₈H₁₇NO₂*C₁₁H₁₃NO₆S
• Synonyms: C₈H₁₇NO₂*C₁₁H₁₃NO₆S
• CAS NO: 1165869-58-8
• Molecular Weight: 446.522
• Mol File: 1165869-58-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₈H₁₇NO₂*C₁₁H₁₃NO₆S(CAS DataBase Reference)
• NIST Chemistry Reference: C₈H₁₇NO₂*C₁₁H₁₃NO₆S(1165869-58-8)
• EPA Substance Registry System: C₈H₁₇NO₂*C₁₁H₁₃NO₆S(1165869-58-8)

Safety Data

• Hazardous Substances Data: 1165869-58-8(Hazardous Substances Data)

Upstream product

• 20531-36-6 2-(benzenesulfonyl)-L-glutamic acid 
• 128013-69-4 (R,S)-3-iso-butyl-4-aminobutyric acid 

Downstream Products

• 148553-50-8 pregabilin 

Relevant articles and documents

NEW PROCESS FOR RESOLVING S-3- (AMINOMETHYL)-5-METHYLHEXANOIC ACID

The present invention relates to a process for resolving S-3-(Aminomethyl)-5-methylhexanoic acid, which adopts benzoyl-L-glutamic acid, 4-methyl benzoyl-L-glutamic acid, benzene sulfonyl-L-glutamic acid or 4-methyl benzene sulfonyl-L-glutamic acid as a resolution agent to make a first resolution to racemic 3-aminomethyl-5-methylhexanoic acid, and adopts the resolution agent same to that of the first resolution to make a second resolution to the first resolution product to obtain the second resolution product, thus the resolution salt product is obtained, and further hydrolyzed by an acid, the resolution agent is extracted to be separated, the pH is adjusted to be neutral, the product S-3-(Aminomethyl)-5-methylhexanoic acid, i.e. the pregabalin, is then precipitated by distillation, therefore the present invention has the characteristics of polluting the environment slightly, high efficiency and stability, simpleness and practicality, producing product with high purity and a low sproduction cost, and is suitable for large-scale production.