1169517-12-7Relevant articles and documents
Synthesis and in vivo influenza virus-inhibitory effect of ester prodrug of 4-guanidino-7-O-methyl-Neu5Ac2en
Honda, Takeshi,Kubo, Shuku,Masuda, Takeshi,Arai, Masami,Kobayashi, Yoshiyuki,Yamashita, Makoto
, p. 2938 - 2940 (2009)
A series of ester prodrugs of 7-O-methyl derivative of Zanamivir (compound 3) was synthesized and their efficacy was evaluated in an influenza infected mice model by intranasal administration. Compound 7c (CS-8958), octanoyl ester prodrug of the C-9 alcoh