1170321-78-4 Usage
Description
(3-endo)-3-(Phenylsulfonyl)-N-[4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]octane-8-carboxamide is a complex organic compound characterized by its unique molecular structure. It is a derivative of 8-azabicyclo[3.2.1]octane, featuring a phenylsulfonyl group at the 3-position and a trifluoromethylphenyl group at the N-position. (3-endo)-3-(Phenylsulfonyl)-N-[4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]octane-8-carboxamide is known for its specific interactions with biological targets, making it a potential candidate for various applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
(3-endo)-3-(Phenylsulfonyl)-N-[4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]octane-8-carboxamide is used as an inhibitor for long chain fatty acid elongase 6 (ELOVL6). This application is significant because ELOVL6 plays a crucial role in the elongation of long-chain fatty acids, which are essential components of cell membranes and signaling molecules. Inhibition of ELOVL6 can have therapeutic implications in various diseases, including certain types of cancer and metabolic disorders, by disrupting the synthesis of these fatty acids and affecting cellular processes.
The compound's ability to target ELOVL6 makes it a valuable tool in the development of novel therapeutic strategies for conditions where the inhibition of fatty acid elongation can be beneficial. Further research and development are necessary to fully understand the potential applications and optimize the compound's efficacy and safety profile for clinical use.
Check Digit Verification of cas no
The CAS Registry Mumber 1170321-78-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,0,3,2 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1170321-78:
(9*1)+(8*1)+(7*7)+(6*0)+(5*3)+(4*2)+(3*1)+(2*7)+(1*8)=114
114 % 10 = 4
So 1170321-78-4 is a valid CAS Registry Number.
1170321-78-4Relevant articles and documents
Synthesis and biological evaluation of a novel 3-sulfonyl-8-azabicyclo[3.2. 1]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors
Nagase, Tsuyoshi,Takahashi, Toshiyuki,Sasaki, Takahide,Nagumo, Akira,Shimamura, Ken,Miyamoto, Yasuhisa,Kitazawa, Hidefumi,Kanesaka, Maki,Yoshimoto, Ryo,Aragane, Katsumi,Tokita, Shigeru,Sato, Nagaaki
supporting information; experimental part, p. 4111 - 4114 (2010/02/17)
Long chain fatty acid elongase 6 (ELOVL6) catalyzes the elongation of long chain fatty acyl-CoAs and is a potential target for the treatment of metabolic disorders. The ultrahigh throughput screen of our corporate chemical collections resulted in the iden