117253-04-0Relevant articles and documents
Synthesis of a sialyl Lewis x mimic with fixed carboxylic acid group: Chemical approach toward the elucidation of the bioactive conformation of sialyl Lewis x
Thoma, Gebhard,Schwarzenbach, Franz,Duthaler, Rudolf O.
, p. 514 - 524 (2007/10/03)
The relation of the solution and bioactive conformation of sialyl Lewis x (sLe(x)) has been addressed by chemical means. To mimic the preferred solution conformation of sLe(x) 1, the more rigid analog 2 has been designed and synthesized. The sialic acid r