117554-90-2Relevant articles and documents
Condensed 1,8-Naphthyridines: Part VIII - Synthesis of 2-Arylpyrimidonaphthyridin-4(3H)-ones
Rajendar Reddy, K.,Mogilaiah, K.,Sreenivasulu, B.
, p. 1194 - 1196 (2007/10/02)
2-Arylpyrimidonaphthyridin-4(3H)-ones (III) have been synthesized (i) by oxidation of 2,3-dihydro-2-arylpyrimidonaphthyridin-4(1H)-ones (II) with nitrobenzene-acetic acid, which in turn have been obtained by the condensation of 2-amino-1,8-naphthyridine-3-carboxamide (I) with aromatic aldehydes in gl. acetic acid, and (ii) by the condensation of 2-amino-1,8-naphthyridine-3-carboxamide (I) with either aromatic aldehydes in nitrobenzene-acetic acid or schiff bases in gl. acetic acid.The structural assignments of all the products are based on elemental analyses and spectral (IR, mass and PMR) data.