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117607-01-9

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117607-01-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 117607-01-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,6,0 and 7 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 117607-01:
(8*1)+(7*1)+(6*7)+(5*6)+(4*0)+(3*7)+(2*0)+(1*1)=109
109 % 10 = 9
So 117607-01-9 is a valid CAS Registry Number.

117607-01-9Downstream Products

117607-01-9Relevant articles and documents

Cardiotonic Agents. 9. Synthesis and Biological Evaluation of a Series of (E)-4,5-Dihydro-6-ethenyl>-3(2H)-pyridazinones: A Novel Class of Compounds with Positive Inotropic, Antithrombotic, and Vasodilatory Activities for the Treatment of Congestive ...

Sircar, I.,Steffen, R. P.,Bobowski, G.,Burke, S. E.,Newton, R. S.,et al.

, p. 342 - 350 (2007/10/02)

A novel series of analogues of (E)-4,5-dihydro-6-ethenyl>-3(2H)-pyridazinone was synthesized as a variation on the imazodan series.The compounds were evaluated for (i) hemodynamic activity, (ii) cyclic AMP-phosphodiesterase inhibitory activity (human platelets and guinea pig heart tissue), and (iii) platelet aggregation inhibitory activity.The insertion of the ethenyl moiety between the phenyl and dihydropyridazinone rings produced novel compounds that retained the potent inotropic / vasodilator activity of the parent imazodan series and enhanced the platelet aggregation inhibition potency.Compound 3d, the most potent in this series, demonstrated in vivo antithrombotic activity.The synthesis and the biological activity of these new pyridazinone analogues are reported.

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