117620-85-6 Usage
Description
Defluoro Levofloxacin, also known as L360000 or Levofloxacin USP Related Compound F, is a nonfluorinated analog of Levofloxacin. It is an off-white to yellow solid and is derived from the fluoroquinolone class of antibiotics. Defluoro Levofloxacin exhibits potent antimicrobial activity and is being explored for its potential applications in various fields due to its unique properties.
Uses
Used in Pharmaceutical Industry:
Defluoro Levofloxacin is used as an active pharmaceutical ingredient for the development of new antibiotics. Its application reason is to provide an alternative to traditional fluoroquinolones, potentially offering a more targeted approach to treating bacterial infections with reduced side effects and lower resistance development.
Used in Research and Development:
In the field of research and development, Defluoro Levofloxacin is used as a chemical probe to study the mechanisms of action and resistance patterns of fluoroquinolone antibiotics. Its application reason is to enhance understanding of bacterial resistance and to aid in the design of more effective antimicrobial agents.
Used in Drug Synthesis:
Defluoro Levofloxacin serves as a key intermediate in the synthesis of novel fluoroquinolone derivatives. Its application reason is to facilitate the development of new drugs with improved pharmacological properties, such as enhanced potency, selectivity, and reduced toxicity.
Used in Veterinary Medicine:
Defluoro Levofloxacin is used as a veterinary drug for the treatment of bacterial infections in animals. Its application reason is to provide an effective alternative to conventional antibiotics, ensuring the health and well-being of animals while minimizing the risk of antibiotic resistance development in the veterinary sector.
Check Digit Verification of cas no
The CAS Registry Mumber 117620-85-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,6,2 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 117620-85:
(8*1)+(7*1)+(6*7)+(5*6)+(4*2)+(3*0)+(2*8)+(1*5)=116
116 % 10 = 6
So 117620-85-6 is a valid CAS Registry Number.
117620-85-6Relevant articles and documents
Synthesis and biological testing of non-fluorinated analogues of Levofloxacin
Gray, Jeffrey L.,Almstead, Ji-In K.,Gallagher, Corey P.,Hu, X. Eric,Kim, Nick K.,Taylor, Cynthia J.,Twinem, Tracy L.,Wallace, Cynthia D.,Ledoussal, Benoit
, p. 2373 - 2375 (2003)
Quinolones without the usual 6-fluorine substituent have been recently described as potent antibacterial agents. A series of non-fluorinated analogues of the antibacterial quinolone Levofloxacin were synthesized and tested.
