117751-44-7Relevant articles and documents
Chemistry of Novel Compounds with Multifunctional Carbon Structure. 5. Molecular Design of Versatile Building Blocks for Aliphatic Monofluoro Molecules by Manipulation of Multifunctional Carbon Structure
Takeuchi, Yoshio,Nagata, Kazuhiro,Koizumi, Toru
, p. 5453 - 5459 (1989)
Three kinds of doubly functionalized monofluoromethylene fragments, 1-fluoro-1-nitro-1-(phenylsulfonyl)alkanes (10), 2-fluoro-2-(phenylsulfonyl)alkanoic esters (11), and 2-fluoro-2-nitroalkanoic esters (12), potentially versatile building blocks for the general synthesis of various aliphatic monofluoro molecules, were prepared from the corresponding difunctional compounds 1-3 by monoalkylation (R) and selective fluorinations.The interconversion or reductive removal of each functional group in 10-12 followed by the introduction of the second alkyl groups (R') at the fluorine-bearing carbon atom was examined.Compounds 12 proved to be useful and practical building blocks for conversions to the various monofluoroalkanes 20-26.
Chemistry of Novel Compounds with Multifunctional Carbon Structure. Part 2. The First Example of Optically Active Multifunctional Carbon Compounds
Takeuchi, Yoshio,Asahina, Masahiro,Nagata, Kazuhiro,Koizumi, Toru
, p. 2203 - 2207 (2007/10/02)
Synthesis of optically active tetrafunctional carbon compounds, (+)- and (-)-fluoronitro(phenylthio)acetates (1), has been achieved for the first time by a repeated transesterification method using titanium alkoxides.The fluorine-containing trifunctional
