118460-12-1

Basic information

• Product Name: (S)-4-benzyl-6-methylmorpholin-2-one
• CAS NO: 118460-12-1
• Molecular Weight: 205.257
• Mol File: 118460-12-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-4-benzyl-6-methylmorpholin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-benzyl-6-methylmorpholin-2-one(118460-12-1)
• EPA Substance Registry System: (S)-4-benzyl-6-methylmorpholin-2-one(118460-12-1)

Safety Data

• Hazardous Substances Data: 118460-12-1(Hazardous Substances Data)

Upstream product

• 357165-43-6 (S)-1-(benzylamino)propan-2-ol 
• 96-32-2 bromoacetic acid methyl ester 
• 103808-45-3 (S)-N-benzyl-2-hydroxypropionamide 
• 100-46-9 benzylamine 

Downstream Products

• 118460-17-6 N-benzyl-N-(S)-(2-hydroxypropyl)-N'-(1-phenylethyl)-glycinamide 

Relevant articles and documents

Nucleophilic Ring-Opening Reactions of Morpholin-2-ones. A Resolution of dl-(Secondary-alkyl)amines

The alcoholysis of morpholin-2-ones yielded an equilibrium mixture of morpholin-2-one and the corresponding hydroxy ester.The equilibrium constants for the methanolysis of several sustituted morpholin-2-ones were determined.Treatment of optically active morpholin-2-ones with (secondary-alkyl)amines resulted in stereoselective ring opening to afford hydroxy amides with up to 30percent de.Hydrolysis of one such hydroxy amide regenerated the optically active (secondary-alkyl)amine and the morpholin-2-one.