1185132-92-6

Basic information

• Product Name: NORFLUOXETINE-D5 HYDROCHLORIDE
• Synonyms: NORFLUOXETINE-D5 HYDROCHLORIDE;γ-[4-(TrifluoroMethyl)phenoxy]benzenepropanaMine
• CAS NO: 1185132-92-6
• Molecular Formula: C16H17ClF3NO
• Molecular Weight: 331.7604896
• Product Categories: Isotope Labeled Compounds;Metabolites & Impurities;Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
• Mol File: 1185132-92-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 145-147°C
• Appearance: /
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility: Aqueous Base (Slightly), Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (
• CAS DataBase Reference: NORFLUOXETINE-D5 HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: NORFLUOXETINE-D5 HYDROCHLORIDE(1185132-92-6)
• EPA Substance Registry System: NORFLUOXETINE-D5 HYDROCHLORIDE(1185132-92-6)

Safety Data

• Hazardous Substances Data: 1185132-92-6(Hazardous Substances Data)

Usage

Description

Norfluoxetine-d5 Hydrochloride is a labeled metabolite of Fluoxetine, a selective serotonin reuptake inhibitor (SSRI) commonly used as an antidepressant. It is a white solid and is utilized in various applications due to its chemical properties and association with Fluoxetine.

Uses

Used in Pharmaceutical Industry:
Norfluoxetine-d5 Hydrochloride is used as a reference material for the development and validation of analytical methods in the pharmaceutical industry. Its application is crucial for ensuring the accurate quantification of Fluoxetine and its metabolites in biological samples, which aids in understanding the drug's pharmacokinetics and pharmacodynamics.
Used in Research and Development:
Norfluoxetine-d5 Hydrochloride is used as a stable isotope-labeled internal standard in research and development for the synthesis, purification, and quality control of Fluoxetine and its analogs. This helps in the development of new antidepressant drugs and the improvement of existing ones.
Used in Toxicology and Forensic Analysis:
Norfluoxetine-d5 Hydrochloride is used as a labeled compound in toxicology and forensic analysis to identify and quantify Fluoxetine in biological samples. This is essential for determining the presence of the drug in cases of overdose, drug interactions, or criminal investigations.
Used in Neuropharmacology Studies:
Norfluoxetine-d5 Hydrochloride is used as a research tool in neuropharmacology to study the effects of Fluoxetine on the serotonin system. This helps in understanding the mechanisms of action of SSRIs and their role in treating various psychiatric disorders.