1186316-72-2Relevant articles and documents
Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas
Hart, Terance,Macias, Alba T.,Benwell, Karen,Brooks, Teresa,D'Alessandro, Jalanie,Dokurno, Pawel,Francis, Geraint,Gibbons, Ben,Haymes, Timothy,Kennett, Guy,Lightowler, Sean,Mansell, Howard,Matassova, Natalia,Misra, Anil,Padfield, Anthony,Parsons, Rachel,Pratt, Robert,Robertson, Alan,Walls, Steven,Wong, Melanie,Roughley, Stephen
supporting information; experimental part, p. 4241 - 4244 (2010/04/02)
We report the discovery of a novel, chiral azetidine urea inhibitor of Fatty Acid Amide Hydrolase (FAAH,) and describe the surprising species selectivity of VER-156084 versus rat and human FAAH and also hCB1.