1186430-85-2Relevant articles and documents
Organocatalytic asymmetric synthesis of polyfunctionalized cyclohexene-carbaldehydes via dominom reaction between 3-(benzyloxy)propanal and β-nitroalkenes
Jiang, Hong-tao,Jiang, Qun,Ge, Cheng-sheng
, p. 2355 - 2359 (2017/05/29)
A novel domino Michael/retro-oxa-Michael/Michael/Aldol condensation reaction was developed via the reaction of 3-(benzyloxy)propanal with β-nitroalkenes catalyzed by secondary amine. Using this methodology, optically pure polyfunctionalized cyclohexene-carbaldehydes were prepared straightforwardly from two simple starting materials in good yield with excellent stereoselectivity.