1187193-67-4

Basic information

• Product Name: (Z)-1,1,1-trifluoro-3-phenylprop-2-en-2-yl diphenylphosphinate
• Synonyms: (Z)-1,1,1-trifluoro-3-phenylprop-2-en-2-yl diphenylphosphinate
• CAS NO: 1187193-67-4
• Molecular Weight: 388.326
• Mol File: 1187193-67-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-1,1,1-trifluoro-3-phenylprop-2-en-2-yl diphenylphosphinate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-1,1,1-trifluoro-3-phenylprop-2-en-2-yl diphenylphosphinate(1187193-67-4)
• EPA Substance Registry System: (Z)-1,1,1-trifluoro-3-phenylprop-2-en-2-yl diphenylphosphinate(1187193-67-4)

Safety Data

• Hazardous Substances Data: 1187193-67-4(Hazardous Substances Data)

Upstream product

• 350-92-5 1,1,1-Trifluoro-3-phenylpropan-2-one 
• 1499-21-4 Diphenylphosphinic chloride 

Relevant articles and documents

Highly selective iridium-catalyzed asymmetric hydrogenation of trifluoromethyl olefins: A new route to trifluoromethyl-bearing stereocenters

Fluorine-containing compounds are useful in many applications ranging from pharmaceuticals to ferroelectric crystals. We have developed a new, highly enantioselective synthetic route to trifluoromethyl-bearing stereocenters in up to 96% ee via asymmetric hydrogenation using N,P-ligated iridium catalysts. We also hydrogenated an isomeric mixture of olefins; this reaction gave the hydrogenation product highly enantioselectively (87% ee), and only the E isomer was present after the reaction had reached 56% conversion.