118722-54-6 Usage
Description
2-(ALLYLDIMETHYLSILYL)PYRIDINE, 90% is an organic compound with the chemical structure of a pyridine ring attached to an allyl group and a dimethylsilyl group. It is a versatile reagent used in various chemical reactions and synthesis processes due to its unique structure and reactivity.
Uses
Used in Chemical Synthesis:
2-(ALLYLDIMETHYLSILYL)PYRIDINE, 90% is used as a pyridyl transfer reagent for the preparation of substituted pyridine derivatives. This application is facilitated by its reaction with various aryl iodides in the presence of a palladium catalyst and silver(I) oxide activator, allowing for the formation of a wide range of pyridine-based compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(ALLYLDIMETHYLSILYL)PYRIDINE, 90% is used as a coupling reagent in the allylation of carbonyl compounds. This process is typically carried out using a copper catalyst, which enables the formation of allyl-containing compounds that can be further utilized in the development of pharmaceutical products.
Used in Organic Chemistry Research:
2-(ALLYLDIMETHYLSILYL)PYRIDINE, 90% is also used in organic chemistry research as a valuable building block for the synthesis of complex organic molecules. Its unique structure allows for various functional group transformations and reactions, making it a useful tool for chemists in the design and synthesis of novel compounds with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 118722-54-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,7,2 and 2 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 118722-54:
(8*1)+(7*1)+(6*8)+(5*7)+(4*2)+(3*2)+(2*5)+(1*4)=126
126 % 10 = 6
So 118722-54-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H15NSi/c1-4-9-12(2,3)10-7-5-6-8-11-10/h4-8H,1,9H2,2-3H3
118722-54-6Relevant articles and documents
CO2 Conversion into Esters by Fluoride-Mediated Carboxylation of Organosilanes and Halide Derivatives
Frogneux, Xavier,Von Wolff, Niklas,Thuéry, Pierre,Lefèvre, Guillaume,Cantat, Thibault
, p. 2930 - 2934 (2016)
A one-step conversion of CO2 into heteroaromatic esters is presented under metal-free conditions. Using fluoride anions as promoters for the C-Si bond activation, pyridyl, furanyl, and thienyl organosilanes are successfully carboxylated with CO2 in the presence of an electrophile. The mechanism of this unprecedented reaction has been elucidated based on experimental and computational results, which show a unique catalytic influence of CO2 in the C-Si bond activation of pyridylsilanes. The methodology is applied to 18 different esters, and it has enabled the incorporation of CO2 into a polyester material for the first time. Metal free! A novel methodology is described to convert CO2 into heteroaromatic esters in the presence of organosilanes and organic halides using fluoride anions as promoters for the C-Si bond activation (see scheme). CO2 exhibits a unique catalytic influence in the C-Si bond cleavage of pyridylsilanes, serving as a traceless activator.
Copper-catalyzed allylation of carbonyl derivatives using allyl(2-pyridyl)silanes
Kamei, Toshiyuki,Fujita, Kazuyoshi,Itami, Kenichiro,Yoshida, Jun-Ichi
, p. 4725 - 4728 (2007/10/03)
(Chemical Equation Presented) We have developed an efficient copper-catalyzed allylation of carbonyl derivatives using allyl(2-pyridyl) silanes, in which the strong directing effect of the 2-pyridyl group was observed. A useful synthesis and allylation of
