1187306-74-6Relevant articles and documents
Identification of MK-1925: A selective, orally active and brain-penetrable opioid receptor-like 1 (ORL1) antagonist
Kobayashi, Kensuke,Tsujita, Tomohiro,Ito, Hirokatsu,Ozaki, Satoshi,Tani, Takeshi,Ishii, Yasuyuki,Okuda, Shoki,Tadano, Kiyoshi,Fukuroda, Takahiro,Ohta, Hisashi,Okamoto, Osamu
scheme or table, p. 4729 - 4732 (2010/04/29)
Structure-activity relationship studies directed toward improving the metabolic stability of compound 1 resulted in the identification of 3-[5-(3,5-difluorophenyl)-3-({[(1S,3R)-3-fluorocyclopentyl]amino}methyl)-4-methyl-1H-pyrazol-1-yl]propanenitrile 39 (
