1189152-81-5 Usage
Description
(S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate is a pyrrolidine derivative with a molecular formula of C14H20BrNO2. It features a tert-butyl ester functional group and is known for its specific stereochemical properties and biological activities due to its (S)-enantiomer form. This chemical compound serves as a valuable building block in organic chemistry for the synthesis of pharmaceuticals and bioactive molecules, and it is also under investigation for its potential therapeutic applications in treating various medical conditions.
Uses
Used in Pharmaceutical Synthesis:
(S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate is used as a key building block in the synthesis of various pharmaceuticals and bioactive molecules. Its unique structure and functional groups make it a versatile component in the development of new drugs and therapeutic agents.
Used in Drug Development:
In the field of drug development, (S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate is utilized for its potential therapeutic applications. Its specific stereochemistry and biological activities are being studied to explore its efficacy in treating a range of medical conditions, making it an important target for research and development.
Used in Organic Chemistry Research:
(S)-tert-butyl 2-(4-bromophenyl)pyrrolidine-1-carboxylate is also used in organic chemistry research to understand its reactivity, synthesis pathways, and potential applications in creating new chemical entities. This knowledge can contribute to the advancement of organic chemistry and the discovery of novel compounds with useful properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1189152-81-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,9,1,5 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1189152-81:
(9*1)+(8*1)+(7*8)+(6*9)+(5*1)+(4*5)+(3*2)+(2*8)+(1*1)=175
175 % 10 = 5
So 1189152-81-5 is a valid CAS Registry Number.
1189152-81-5Relevant articles and documents
Enantioselective Radical Cyclization for Construction of 5-Membered Ring Structures by Metalloradical C-H Alkylation
Wang, Yong,Wen, Xin,Cui, Xin,Zhang, X. Peter
, p. 4792 - 4796 (2018/04/17)
Radical cyclization represents a powerful strategy for construction of ring structures. Traditional radical cyclization, which is based on radical addition as the key step, necessitates the use of unsaturated substrates. Guided by the concept of metalloradical catalysis, a different mode of radical cyclization that can employ saturated C-H substrates is demonstrated through the development of a Co(II)-based system for catalytic activation of aliphatic diazo compounds for enantioselective radical alkylation of various C(sp3)-H bonds. It allows for efficient construction of chiral pyrrolidines and other valuable 5-membered cyclic compounds. This alternative strategy of radical cyclization provides a new retrosynthetic paradigm to prepare five-membered cyclic molecules from readily available open-chain aldehydes through the union of C-H and C=O elements for C-C bond formation.
