1189749-49-2 Usage
Type
Synthetic chemical compound
Potential applications
Pharmaceutical industry
Properties
Potential anti-inflammatory and anti-cancer properties
Specific content
Ability to inhibit the growth of certain types of cancer cells
Results
Promising results in preclinical studies
Potential
Therapeutic agent for various diseases
Investigation
Potential as a fluorescent probe for detecting and imaging certain biological molecules
Future needs
Further research to fully understand the biological activity and potential medical applications
Check Digit Verification of cas no
The CAS Registry Mumber 1189749-49-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,9,7,4 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1189749-49:
(9*1)+(8*1)+(7*8)+(6*9)+(5*7)+(4*4)+(3*9)+(2*4)+(1*9)=222
222 % 10 = 2
So 1189749-49-2 is a valid CAS Registry Number.
1189749-49-2Relevant articles and documents
N-Bromosuccinimide (NBS)-Catalyzed C-H Bond Functionalization: An Annulation of Alkynes with Electron Withdrawing Group (EWG)-Substituted Acetyl Indoles for the Synthesis of Carbazoles
Wang, Han,Wang, Zhen,Wang, Yi-Long,Zhou, Rui-Rui,Wu, Guang-Chuan,Yin, Si-Yao,Yan, Xu,Wang, Bin
, p. 6140 - 6143 (2017)
An N-bromosuccinimide-catalyzed intermolecular annulation of acetyl indoles with alkynes was developed, allowing for regioselective formation of valuable carbazoles through direct C-H bond functionalization. The readily available catalyst, wide substrate scope, gram scale synthesis, and mild conditions make this method practical. Mechanistic investigations indicate that the bromination of acetyl indole takes place to generate a bromide intermediate, followed by coupling with an alkyne and intramolecular cycloaromatization to furnish carbazole products.
