1189787-97-0Relevant articles and documents
Indolobenzazepin-7-ones and 6-, 8-, and 9-membered ring derivatives as tubulin polymerization inhibitors: Synthesis and structure-activity relationship studies
Putey, Aurélien,Popowycz, Florence,Do, Quoc-Tuan,Bernard, Philippe,Talapatra, Sandeep K.,Kozielski, Frank,Galmarini, Carlos M.,Joseph, Beno?t
experimental part, p. 5916 - 5925 (2010/03/24)
Several small weight indole derivatives (D-64131, D-24851, BPR0L075, BLF 61-3, and ATI derivatives) are potent tubulin polymerization inhibitors and show nanomolar antiproliferative activity. Among them, indolobenzazepin-7-ones were recently disclosed as