1190305-14-6

Basic information

• Product Name: N-caffeoyl serotonin
• Synonyms: N-caffeoyl serotonin
• CAS NO: 1190305-14-6
• Molecular Weight: 338.363
• Mol File: 1190305-14-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-caffeoyl serotonin(CAS DataBase Reference)
• NIST Chemistry Reference: N-caffeoyl serotonin(1190305-14-6)
• EPA Substance Registry System: N-caffeoyl serotonin(1190305-14-6)

Safety Data

• Hazardous Substances Data: 1190305-14-6(Hazardous Substances Data)

Upstream product

• 139-85-5 3,4-dihydroxybenzaldehyde 
• 71186-67-9 3,4-diallyloxybenzaldehyde 
• 200059-78-5 3-(3,4-bis-allyloxyphenyl)acrylic acid 

Downstream Products

• 1383814-06-9 C₁₉H₂₀N₂O₄ 

Relevant articles and documents

Synthesis and structure-activity relationships of phenylpropanoid amides of serotonin on tyrosinase inhibition

In this manuscript, we synthesized a series of phenylpropanoid amide of serotonin 1-9, analyzed their structural importance for two biologic activities (antioxidant activity and tyrosinase inhibitory activity). While the serotonin moiety and the amide linkage of serotonin derivatives affect antioxidant activity strongly, the serotonin moiety, the amide linkage and the cinnamic acid moiety affect tyrosinase inhibitory activity. Among tested compounds, compound 4 which contains cathechol moiety exhibited the most antioxidant activity (EC50 = 19.4 ± 2.0 μM), and compound 6 exhibited significant tyrosinase inhibitory activity (IC50 = 5.4 ± 3.6 μM). Our data suggests that a useful clue for the design and development of new tyrosinase inhibitors.

Synthesis and structure-activity relationships of serotonin derivatives effect on α-glucosidase inhibition

The α-glucosidase inhibitory activities of serotonin derivatives were evaluated. Two serotonin derivatives, N-p-coumaroyl serotonin (2) and N-caffeoyl serotonin (4) exhibited most potent inhibition on α-glucosidase, whereas, cinnamic acid derivatives were