119198-12-8

Basic information

• Product Name: N-Methyl-N-(5-nitrobenzofur-2-ylmethyl)-4-nitrophenethylamine
• Synonyms: N-Methyl-N-(5-nitrobenzofur-2-ylmethyl)-4-nitrophenethylamine
• CAS NO: 119198-12-8
• Molecular Weight: 355.35
• Mol File: 119198-12-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-Methyl-N-(5-nitrobenzofur-2-ylmethyl)-4-nitrophenethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Methyl-N-(5-nitrobenzofur-2-ylmethyl)-4-nitrophenethylamine(119198-12-8)
• EPA Substance Registry System: N-Methyl-N-(5-nitrobenzofur-2-ylmethyl)-4-nitrophenethylamine(119198-12-8)

Safety Data

• Hazardous Substances Data: 119198-12-8(Hazardous Substances Data)

Upstream product

• 118679-18-8 2-bromomethyl-5-nitro-benzofuran 
• 85176-37-0 N-methyl-N-[2-(4-nitro-phenyl)-ethyl]-amine 

Relevant articles and documents

Sulfonamide anti-arrhythmic agents

A series of novel N-alkyl-N-(alkanesulphonamidoheterocyclicmethyl)-4-alkanesulphonamidophenetyl mines have been prepared, including their pharmaceutically acceptable salts and various key novel intermediates therefor. The heterocyclic moiety present in these compounds is a benzo-fused heterocyclic group derived from either benzofuran, benzothiophene, benzoxazole or quinoline, and it is attached to the adjacent methyl group of the molecule by means of the available ring carbon atom which is situated alpha to the hetero atom. These particular compounds are useful in therapy as highly effective anti-arrhythmic agents and therefore, are of value in the treatment of various cardiac arrhythmias. Preferred member compounds include N-methyl-N-(5-methanesulphonamidobenzofur-2-ylmethyl)-4-methanesulphonamidop henethylamine and N-methyl-N-(6-methanesulphonamidoquinol-2-ylmethyl)-4-methanesulphonamidophen thylamine. Methods for preparing all these compounds from known starting materials are provided.