1192167-43-3Relevant articles and documents
Lewis Acid Catalyzed Cyclization of Propargylic Alcohols with 2-Vinylphenol
Han, Ya-Ping,Song, Xian-Rong,Qiu, Yi-Feng,Li, Xue-Song,Zhang, Heng-Rui,Zhu, Xin-Yu,Liu, Xue-Yuan,Liang, Yong-Min
, p. 3866 - 3869 (2016)
An unprecedented Lewis acid catalyzed, protection-free, and high-efficiency synthesis of valuable 3,4-dihydro-2H-2,4-methanochromans via cycloaddition of propargylic alkynols with 2-vinylphenol is described. This cycloaddition protocol, which tolerates a
Lewis-Acid-Catalyzed Tandem Cyclization by Ring Expansion of Tertiary Cycloalkanols with Propargyl Alcohols
Kong, Xiangtao,Li, Xue-Song,Li, Yuke,Liang, Yong-Min,Liu, Hong-Chao,Niu, Zhi-Jie,Wang, Cui-Tian,Wei, Wan-Xu,Zhang, Zhe
supporting information, p. 9457 - 9462 (2021/12/14)
A new method for the efficient synthesis of hexahydro-1H-fluorene and octahydrobenzo[a]azulene derivatives through a ring-expansion strategy is reported. With an appropriate combination of thulium(III) trifluoromethanesulfonate and 13X molecular sieves, a range of unsaturated polycyclic compounds were obtained in good yields. Mechanism studies reveal that the reaction is more likely to undergo Meyer–Schuster rearrangement, ring expansion, and Friedel–Crafts-type pathways, which provide a conceptually different strategy for the ring opening of tertiary cycloalkanols.
Br?nsted Acid-Mediated Formal [3+3] Annulation Between Propargylic Alcohols and 1,3-Diketones
Han, Ya-Ping,Li, Xue-Song,Zhu, Xin-Yu,Sun, Zhou,Li, Ming,Wang, Yu-Zhao,Liang, Yong-Min
supporting information, p. 870 - 874 (2017/12/26)
A Br?nsted acid-mediated formal [3+3] cascade annulation of propargylic alcohols with 1,3-diketones proceeds through a sequential Meyer?Schuster rearrangement/1,2-addition. This protocol, which has a wide scope and is conducted under an ambient atmosphere