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119240-35-6

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119240-35-6 Usage

Chemical structure

A chemical compound derived from the sugar D-ribose, with three acetyl groups (-COCH3) attached to the hydroxyl groups at the 1, 2, and 3 positions of the ribose ring.

Appearance

A white crystalline solid.

Solubility

Soluble in organic solvents, such as chloroform, methanol, and acetone.

Synthesis

Used in the synthesis of nucleoside analogs and other biologically active compounds.

Protecting group

Often employed as a protecting group for the hydroxyl groups on the ribose ring, allowing for selective chemical reactions to be carried out at specific positions on the molecule.

Organic chemistry research

Utilized as a model compound for studying reaction mechanisms.

Building block

Used as a building block for the creation of more complex molecules in organic chemistry.

Applications

Widely used in the pharmaceutical industry for the development of new drugs, particularly in the field of antiviral and anticancer agents.

Stability

Relatively stable under normal laboratory conditions, but sensitive to acidic and basic conditions, which can lead to deprotection or hydrolysis of the acetyl groups.

Purification

Typically purified by recrystallization from an appropriate solvent, such as ethanol or a mixture of ethanol and water.

Check Digit Verification of cas no

The CAS Registry Mumber 119240-35-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,2,4 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 119240-35:
(8*1)+(7*1)+(6*9)+(5*2)+(4*4)+(3*0)+(2*3)+(1*5)=106
106 % 10 = 6
So 119240-35-6 is a valid CAS Registry Number.

119240-35-6Relevant articles and documents

Lipase-catalyzed regio- and stereoselective deacylation: Separation of anomers of peracylated α,β-D-ribofuranosides

Sharma, Raman K.,Aggarwal, Neha,Arya, Anu,Olsen, Carl E.,Parmar, Virinder S.,Prasad, Ashok K.

experimental part, p. 1727 - 1731 (2011/03/19)

Efficient regio- and stereoselective deacylation of acyloxy function involving C-5′ hydroxyl group of α-anomer over the other similar C-5′ acyl group of β-anomer and acyl groups involving secondary hydroxyls in anomeric mixture of peracylates of D-ribose has been achieved during deacylation reaction mediated by Lipozyme TL IM (Thermomyces lanuginosus lipase immobilized on silica). This enzymatic methodology has been efficiently used for the separation of anomeric mixtures of peracylated α,β-D-ribofuranosides.

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