1194476-66-8

Basic information

• Product Name: (3R,4S)-3-benzoyl-4-ethyl-7-methoxychroman-2-one
• Synonyms: (3R,4S)-3-benzoyl-4-ethyl-7-methoxychroman-2-one
• CAS NO: 1194476-66-8
• Molecular Weight: 310.35
• Mol File: 1194476-66-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4S)-3-benzoyl-4-ethyl-7-methoxychroman-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4S)-3-benzoyl-4-ethyl-7-methoxychroman-2-one(1194476-66-8)
• EPA Substance Registry System: (3R,4S)-3-benzoyl-4-ethyl-7-methoxychroman-2-one(1194476-66-8)

Safety Data

• Hazardous Substances Data: 1194476-66-8(Hazardous Substances Data)

Upstream product

• 64267-12-5 7-(methyloxy)-3-(phenylcarbonyl)-2H-chromen-2-one 
• 97-93-8 triethylaluminum 

Relevant articles and documents

Asymmetric conjugate additions to 1,1′-diactivated cyclic enones-a comparative study

A study of copper-phosphoramidite-catalysed ZnR2 and AlR3 additions to 1,1′-dicarbonyl-activated cyclic Michael acceptors has revealed high enantioselectivities for AlR3 (R = Me, Et) 1,4-addition to a range of 3-acylcoumarins (85-98% ee, trans:cis ～90:10) using commercial or readily available ligands. Large substituents at the 6-position, and to some extent at the 5-position, of the coumarin are less well tolerated, nor is truncation of the coumarin motif to a comparable 2-acylcyclohexenone (ee values up to 78%).