1195752-72-7

Basic information

• Product Name: C₃₂H₄₄N₁₀O₁₄
• CAS NO: 1195752-72-7
• Molecular Weight: 792.76
• Mol File: 1195752-72-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₂H₄₄N₁₀O₁₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₂H₄₄N₁₀O₁₄(1195752-72-7)
• EPA Substance Registry System: C₃₂H₄₄N₁₀O₁₄(1195752-72-7)

Safety Data

• Hazardous Substances Data: 1195752-72-7(Hazardous Substances Data)

Upstream product

• 214750-75-1 Fmoc-D-Lysine(Alloc)-OH 
• 29022-11-5 N-(fluoren-9-ylmethoxycarbonyl)glycine 
• 71989-14-5 N-(9-fluorenylmethoxycarbonyl)-4-O-tert-butyl-D-aspartic acid 
• 144120-53-6 (S)-3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-(allyloxy)-4-oxobutanoic acid 
• 268729-12-0 (2S,4R)-4-tert-butoxy-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid 
• 136590-09-5 (S)-3-(3-nitro-4-hydroxyphenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propionic acid 

Relevant articles and documents

Structure - Activity relationship studies of targeting ligands against breast cancer cells

A series of LXY3 (1) analogues were designed and synthesized. Their binding affinity was demonstrated using MDA-MB-231 breast cancer cells adherence inhibition assay. Further structure-activity relationship was obtained. Analogue 29 was discovered to have 3.5-fold increase of the binding affinity. Fluorescent microscopy and in vivo and ex vivo imaging studies demonstrated that 29 is an efficient in vivo targeting agent against α3 integrin of MDA-MB-231 breast tumor xenograft implant. 2009 American Chemical Society.