119642-28-3

Basic information

• Product Name: 3-amino-2-hydroxy-4-phenylbutyric acid hydrochloride
• CAS NO: 119642-28-3
• Molecular Weight: 231.679
• Mol File: 119642-28-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-amino-2-hydroxy-4-phenylbutyric acid hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-2-hydroxy-4-phenylbutyric acid hydrochloride(119642-28-3)
• EPA Substance Registry System: 3-amino-2-hydroxy-4-phenylbutyric acid hydrochloride(119642-28-3)

Safety Data

• Hazardous Substances Data: 119642-28-3(Hazardous Substances Data)

Upstream product

• 115186-33-9 (R)-tert-butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate 
• 18942-49-9 Boc-D-Phe-OH 
• 77119-85-8 N-(tert-butoxycarbonyl)-D-phenylalaninal 
• 128223-46-1 methyl (R)-N-(isopropoxycarbonyl)phenylalaninate 
• 128223-47-2 (R)-N-(isopropoxycarbonyl)phenylalaninol 
• 13033-84-6 D-phenylalanine methyl ester hydrochloride 
• 673-06-3 D-(R)-phenylalanine 
• 129867-99-8 (3-R)-2-acetoxy-3-isopropoxycarbonylamino-4-phenylbutyronitrile 
• 129867-98-7 (R)-N-(isopropoxycarbonyl)phenylalaninal 

Downstream Products

• 140409-02-5 methyl (2S,3R)-2-acetoxy-3-acetylamino-4-phenylbutyrate 
• 140409-03-6 methyl (2R,3R)-2-acetoxy-3-acetylamino-4-phenylbutyrate 
• 1356606-78-4 (R)-3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-2-hydroxy-4-phenylbutanoic acid 

Relevant articles and documents

Synthesis of α-Ketoamide-Based Stereoselective Calpain-1 Inhibitors as Neuroprotective Agents

Calpain inhibitors have been proposed as drug candidates for neurodegenerative disorders, with ABT-957 entering clinical trials for Alzheimer's disease and mild cognitive impairment. The structure of ABT-957 was very recently disclosed, and trials were te

A Practical Synthesis of threo-3-Amino-2-hydroxycarboxylic Acids

An expeditious synthesis of (2R,3S)-3-amino-4-cyclohexyl-2-hydroxybutyric acid (2) and (2S,3R)-3-amino-2-hydroxy-4-phenylbutyric acid (4), the key components of the renin inhibitor (1) and bestatin (3), respectively, have been accomplished by featuring hi