119925-07-4

Basic information

• Product Name: (E)-1-methoxy-2-(3-methylbut-1-en-1-yl)benzene
• Synonyms: (E)-1-methoxy-2-(3-methylbut-1-en-1-yl)benzene
• CAS NO: 119925-07-4
• Molecular Weight: 176.258
• Mol File: 119925-07-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-1-methoxy-2-(3-methylbut-1-en-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-methoxy-2-(3-methylbut-1-en-1-yl)benzene(119925-07-4)
• EPA Substance Registry System: (E)-1-methoxy-2-(3-methylbut-1-en-1-yl)benzene(119925-07-4)

Safety Data

• Hazardous Substances Data: 119925-07-4(Hazardous Substances Data)

Upstream product

• 1011-54-7 2-methoxycinnamic acid 
• 135-02-4 ortho-anisaldehyde 
• 917-64-6 methyl magnesium iodide 
• 116972-95-3 2-[(E)-2-(2-Methoxy-phenyl)-vinyl]-[1,3]dithiolane 

Downstream Products

• 4957-19-1 1-methoxy-2-(3-methylbutyl)benzene 
• 143999-39-7 3.5-dinitro-2-hydroxy-1-isopentyl-benzene 
• 5032-03-1 (3-methyl-butyl)-phenol 

Relevant articles and documents

Nickel-Catalyzed Geminal Dimethylation of Allylic Dithioacetals

A geminal dimethyl group is introduced regioselectively in excellent yield from the reactions of allylic dithioacetals and methylmagnesium iodide in the presence of 3 mol percent of NiCl2(dppe) in refluxing ether-benzene.

NiCl2(dppe)-Catalyzed Geminal Dialkylation of Dithioacetals and Trimethylation of Ortho Thioesters

NiCl2(dppe)-catalyzed cross-coupling of cinnamaldehyde dithioacetals gave the corresponding geminal dimethylation products in excellent yields.Allylic ortho thioesters afforded regioselectively the corresponding trimethylation products.The reaction may occur via an 18-electron ?-allyl intermediate, which undergoes facile reductive elimination to afford the geminal dimethylation product.Benzylic dithioacetals having an ortho amino group gave 2-isopropylanilines exclusively.The reaction of benzylic dithioacetals with EtMgBr under the same conditions yielded geminal diethylation products.