119946-74-6

Basic information

• Product Name: C₂₀H₃₂O₇
• Synonyms: C₂₀H₃₂O₇
• CAS NO: 119946-74-6
• Molecular Weight: 384.47
• Mol File: 119946-74-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₃₂O₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₃₂O₇(119946-74-6)
• EPA Substance Registry System: C₂₀H₃₂O₇(119946-74-6)

Safety Data

• Hazardous Substances Data: 119946-74-6(Hazardous Substances Data)

Upstream product

• 53562-86-0 (S)-3-hydroxybutyric acid methyl ester 
• 71939-50-9 dihydroartemisinin 

Relevant articles and documents

Antimalarial activity of new water-soluble dihydroartemisinin derivatives. 2. Stereospecificity of the ether side chain

A new series of hydrolytically stable and water-soluble dihydroartemisinin derivatives with optically active side chains was prepared as potential antimalarial agents. This was an effort to prepare compounds with activity superior to that of artelinic acid and to examine the impact of the stereospecificity of the introduced alkyl side chain on biological properties. The ester derivatives possess superior in vitro activity to artemisinin, artemether, and arteether against two strains of Plasmodium falciparum (D-6 and W-2); however, conversion of the esters to their corresponding acids drastically reduces their antimalarial activity. None of the new acids possess in vitro antimalarial activity superior to that of artelinic acid. Although there appears to be limited stereospecificity for antimalarial activity among the acids (7a-d) tested, significant differences in antimalarial activity was seen among the esters.