1199813-82-5Relevant articles and documents
Initial process development and scale-up of the synthesis of a triple reuptake inhibitor ALB 109780
Yang, Qiang,Ulysse, Luckner G.,McLaws, Mark D.,Keefe, Daniel K.,Haney, Brian P.,Zha, Congxiang,Guzzo, Peter R.,Liu, Shuang
, p. 499 - 506 (2012)
Early process development toward a triple reuptake inhibitor is described. Three different routes were evaluated; one of them was optimized and scaled up to generate 470 g of API as this route minimized the formation of undesired side products. The select
Preparation of tetrahydroisoquinoline-3-ones via cyclization of phenyl acetamides using eaton's reagent
Yang, Qiang,Ulysse Jr., Luckner G.,McLaws, Mark,Keefe, Daniel K.,Guzzo, Peter,Haney, Brian P.
, p. 44 - 54 (2014/04/17)
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