120-29-6 Usage
Chemical Properties
white to slightly yellow crystalline powder
Uses
Different sources of media describe the Uses of 120-29-6 differently. You can refer to the following data:
1. Tropine is an oxidative product of Tropane, used to synthesize alkaloid derivatives.
2. Tropine as an oxidative product of Tropane, used to synthesize alkaloid derivatives. Benzatropine and etybenzatropine are derivatives of tropine. It is also a building block of atropine, an anticholinergic drug prototypical of the muscarinic antagonist class.
Definition
ChEBI: A derivative of tropane having a hydroxy group at the 3-position.
Purification Methods
Distil 3-tropanol in steam and crystallise it from Et2O or toluene/pet ether. It sublimes at 60o/0.1mm. Hygroscopic. The hydrochloride has m 280o (from EtOH/Et2O). [Beilstein 21 H 16, 21 I 197, 21 II 17, 21 III/IV 168, 21/1 V 219.]
Check Digit Verification of cas no
The CAS Registry Mumber 120-29-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 120-29:
(5*1)+(4*2)+(3*0)+(2*2)+(1*9)=26
26 % 10 = 6
So 120-29-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H15NO/c1-9-6-2-3-7(9)5-8(10)4-6/h6-8,10H,2-5H2,1H3
120-29-6Relevant articles and documents
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Hromatka et al.
, p. 1321,1324 (1952)
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Lindenmann
, p. 490,494 (1959)
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Keagle,Hartung
, p. 1608 (1946)
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The synthesis and separation of [3-2H]tropine and [3-2H]pseudotropine (Ψ-tropine)
Bartholomew,Smith,Darcy,Trudgill,Hopper
, p. 85 - 91 (1994)
Tropine was reduced using sodium borodeuteride to give a mixture of the epimers [3-2H]tropine and [3-2H]pseudotropine with the latter compound predominating and constituting about 70% of the mixture. Crystallisation of the product from diethyl ether gave crystals of pure [3-2H]pseudotropine and a supernatant solution containing a mixture of the epimers. Acetylation of this mixture using acetyl chloride preferentially acetylated the pseudotropine and the acetylated products were separated from the tropine by flash chromatography to leave a sample of pure [3-2H]tropine.
CRYSTALLINE ATROPINE SULFATE
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Page/Page column 4-5, (2014/07/21)
The present invention relates to crystalline polymorph form of Atropine sulfate and process for the preparation thereof.