1200863-94-0Relevant articles and documents
A practical synthesis of b-keto thioesters by direct crossed-claisen coupling of thioesters and N-acylbenzotriazoles
Zhou, Guoqiang,Lim, Daniel,Fang, Fang,Coltart, Don M.
experimental part, p. 3350 - 3352 (2010/03/03)
Thioesters undergo chemoselective soft enolization and acylation with N-acylbenzotriazoles on treatment with MgBr2?OEt2 and i-Pr2NEt to give b-keto thioesters. Prior enolate formation is not required and the reaction is conducted using untreated dichlorom