120281-56-3

Basic information

• Product Name: 2-Iodo-5-phenylpyridine
• Synonyms: 2-Iodo-5-phenylpyridine;2-Iodo-5-phenylpypridine;Pyridine,2-iodo-5-phenyl-;2-Iodo-5-Phenylpyridine 2iodo5phenylpypridine;MFCD11044365
• CAS NO: 120281-56-3
• Molecular Formula: C₁₁H₈IN
• Molecular Weight: 281.09
• Mol File: 120281-56-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 104 °C
• Boiling Point: 344°C at 760 mmHg
• Flash Point: 161.8°C
• Appearance: /
• Density: 1.653g/cm³
• Vapor Pressure: 0.000135mmHg at 25°C
• Refractive Index: 1.647
• Storage Temp.: 2-8°C
• PKA: 1.46±0.10(Predicted)
• CAS DataBase Reference: 2-Iodo-5-phenylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Iodo-5-phenylpyridine(120281-56-3)
• EPA Substance Registry System: 2-Iodo-5-phenylpyridine(120281-56-3)

Safety Data

• Hazardous Substances Data: 120281-56-3(Hazardous Substances Data)

Usage

General Description

2-Iodo-5-phenylpyridine is an organoiodine compound with the formula C11H7IN. It is a yellow to light brown solid that is commonly used as a building block in organic synthesis. This molecule contains a pyridine ring with a phenyl group and an iodine atom in the 2 and 5 positions, respectively. 2-Iodo-5-phenylpyridine is often utilized as a reagent for the conversion of alcohols to alkyl iodides and for the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is also known for its potential as a molecular tool in medicinal chemistry and drug discovery research due to its ability to form various chemical bonds with other molecules.

InChI:InChI=1/C11H8IN/c12-11-7-6-10(8-13-11)9-4-2-1-3-5-9/h1-8H

Upstream product

• 66600-05-3 2-chloro-5-phenylpyridine 
• 98-80-6 phenylboronic acid 
• 1072-97-5 5-bromo-2-pyridylamine 
• 33421-40-8 5-phenyl-pyridin-2-ylamine 

Downstream Products

• 572912-40-4 4-(5-phenyl-2-pyridinyl)-3-butan-1-ol 
• 572912-39-1 4-(5-phenyl-2-pyridinyl)-3-butyn-1-ol 

Relevant articles and documents

Preparation of 2-iodo-5-phenyl-pyridine method

The invention provides a method for preparing 2-iodine-5-phenylpyridine and relates to the field of an industrial production technology of 2-iodine-5-phenylpyridine. The method comprises the following steps: selecting 2-chlorine-5-phenylpyridine as an ini

Benzopyran derivatives

Compounds of the formula STR1 wherein R 1 is hydrogen, halogen, trifluoromethyl, nitro, cyano, lower alkyl, lower alkoxycarbonyl, lower alkylthio, lower alkylsulphonyl, lower alkanoyl, aroyl, carbamoyl, mono(lower alkyl)carbamoyl or di(lower alkyl)carbamoyl, R 2 is hydrogen, lower alkyl or phenyl, R 3 is hydrogen or lower alkyl, R 4 and R 5 each is hydrogen or R 4 is hydroxy and R 5 is hydrogen or R 4 and R 5 together are a carbon-carbon bond and R 6 is an aryl or N-heteroaryl group carrying a hydroxy group in the 2-position or, in the case of a N-heteroaryl group, also a N-oxide group in the 2-position, and pharmaceutically acceptable acid addition salts of these compounds of formula I which are basic, possess pronounced potassium channel activating activity and can be used as medicaments, particularly in the control or prevention of hypertension, congestive heart failure, angina pectoris, peripheral and cerebral vascular disease and smooth muscle disorders.