1205553-81-6

Basic information

• Product Name: 3-methyl-4-nitro-5-((2S,3R)-3-nitro-2-phenylbutyl)isoxazole
• Synonyms: 3-methyl-4-nitro-5-((2S,3R)-3-nitro-2-phenylbutyl)isoxazole
• CAS NO: 1205553-81-6
• Molecular Weight: 305.29
• Mol File: 1205553-81-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methyl-4-nitro-5-((2S,3R)-3-nitro-2-phenylbutyl)isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-4-nitro-5-((2S,3R)-3-nitro-2-phenylbutyl)isoxazole(1205553-81-6)
• EPA Substance Registry System: 3-methyl-4-nitro-5-((2S,3R)-3-nitro-2-phenylbutyl)isoxazole(1205553-81-6)

Safety Data

• Hazardous Substances Data: 1205553-81-6(Hazardous Substances Data)

Upstream product

• 79-24-3 Nitroethane 
• 51978-94-0 (E)-3-methyl-4-nitro-5-styrylisoxazole 

Relevant articles and documents

Catalytic asymmetric conjugate addition of nitroalkanes to 4-nitro5-styrylisoxazoles

(Chemical equation presented) Nitro versus nitro: 4-Nitro-5- styrylisoxazoles were used as masked α,β-unsaturated carboxylic acids in the titled catalytic asymmetric transformation. The 4-nitroisoxazole core acts as an activator of the conjugated alkene and a latent carboxylate functionality. The reaction proceeded with 5 mol% of a readily prepared phasetransfer catalyst at room temperature with remarkable diastereo- and enantioselectivity (see scheme).