1206614-04-1Relevant articles and documents
Enantioselective syntheses and X-ray structures of (S)- and (R)-N-norlaudanidine: trace opium constituents
Zein, Ahmed L.,Dakhil, Otman O.,Dawe, Louise N.,Georghiou, Paris E.
experimental part, p. 177 - 180 (2010/03/04)
The enantioselective synthesis of each of the enantiomers of N-norlaudanidine, a minor Papaver somniferum opium benzyltetrahydoisoquinoline alkaloid is described. This was achieved using a chiral auxiliary-mediated Bischler-Napieralski cyclization-sodium borohydride reduction strategy. The X-ray crystal structures of each of these secondary amines are reported.