120821-94-5

Basic information

• Product Name: α,α-diphenyl-2-benzothiazolyl-methanol
• Synonyms: α,α-diphenyl-2-benzothiazolyl-methanol
• CAS NO: 120821-94-5
• Molecular Weight: 317.411
• Mol File: 120821-94-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: α,α-diphenyl-2-benzothiazolyl-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: α,α-diphenyl-2-benzothiazolyl-methanol(120821-94-5)
• EPA Substance Registry System: α,α-diphenyl-2-benzothiazolyl-methanol(120821-94-5)

Safety Data

• Hazardous Substances Data: 120821-94-5(Hazardous Substances Data)

Upstream product

• 119-61-9 benzophenone 
• 39582-59-7 benzothiazol-2-yl-lithium 
• 95-16-9 1,3-Benzothiazole 
• 16622-36-9 α-(2-benzothiazolyl)diphenylmethane 
• 32137-73-8 2-(trimethylsilyl)benzothiazole 

Downstream Products

• 16622-36-9 α-(2-benzothiazolyl)diphenylmethane 

Relevant articles and documents

Reduction of 1,3-azole and 1,3-benzazole carbinols with sodium borohydride-trifluoroacetic acid

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Metal-free deprotonative functionalization of heteroaromatics using organic superbase catalyst

Metal-free deprotonative functionalization of heteroaromatic compounds was achieved using an organic superbase catalyst; an organosilicon additive such as trimethylsilylpropyne was employed for activating the catalytic cycle of 1,2-addition to carbonyl compounds.

Catalytic activation of silylated nucleophiles using tBu-P4 as a base

Trialkylsilyl groups play an important role as effective protecting groups in organic synthesis. Various O, N, and C nucleophilic sites can be protected by trialkylsilyl groups to control the selectivity of reactions. The nucleophilic attack of a fluoride anion on a silyl group is recognized as one of the most useful methods for desilylation. The activation of the nucleophile-silicon bond is important not only for desilylation but also for the generation of a reactive nucleophilic anion to achieve a new bond formation. The phosphazene bases developed by Schwesinger are known to be strong non-metallic organic bases. Among them, the tBu-P4 base has been used for various selective deprotonative transformations, although the ability of tBu-P4 base to activate silylated nucleophiles has not yet been shown. A novel catalytic activation of various O, N, and C nucleophile-silicon bonds using tBu-P4 base was investigated to perform nucleophilic reactions with various electrophiles. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.