1214319-92-2 Usage
Description
N3-PEG8-CH2CH2COOH, also known as Azido-PEG8-acid, is an aqueous soluble PEG (polyethylene glycol) linker that features an azide (N3) group and a terminal carboxylic acid (COOH) group. This versatile molecule is designed to facilitate chemical reactions and conjugations through its functional groups, making it a valuable component in various applications across different industries.
Uses
Used in Bioconjugation:
N3-PEG8-CH2CH2COOH is used as a bioconjugation agent for the formation of stable triazole linkages with alkyne, BCN, and DBCO groups via Click Chemistry. This allows for the efficient and specific attachment of biomolecules, such as peptides, proteins, and other ligands, to create targeted drug delivery systems or for use in research applications.
Used in Drug Delivery Systems:
In the pharmaceutical industry, N3-PEG8-CH2CH2COOH is used as a component in drug delivery systems to improve the solubility, stability, and bioavailability of therapeutic agents. The PEG linker can be attached to drug molecules or nanoparticles, enhancing their circulation time in the body and reducing immunogenicity.
Used in Diagnostic Imaging:
N3-PEG8-CH2CH2COOH is utilized as a contrast agent in diagnostic imaging applications, such as magnetic resonance imaging (MRI) and positron emission tomography (PET). The PEG linker can be conjugated to imaging agents or nanoparticles, improving their stability and biodistribution, and allowing for enhanced imaging of specific tissues or organs.
Used in Cosmetics and Personal Care:
In the cosmetics and personal care industry, N3-PEG8-CH2CH2COOH is used as a skin conditioning agent and emulsifier. The PEG linker can be attached to various cosmetic ingredients, improving their solubility, stability, and efficacy on the skin, as well as providing a smooth and moisturizing texture to the final product.
Used in Material Science:
N3-PEG8-CH2CH2COOH is employed in material science for the development of functional coatings, hydrogels, and other biomaterials. The PEG linker can be used to attach bioactive molecules or other functional groups to the surface of materials, enabling the creation of stimuli-responsive or targeted materials with applications in tissue engineering, sensors, and other areas.
Check Digit Verification of cas no
The CAS Registry Mumber 1214319-92-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,4,3,1 and 9 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1214319-92:
(9*1)+(8*2)+(7*1)+(6*4)+(5*3)+(4*1)+(3*9)+(2*9)+(1*2)=122
122 % 10 = 2
So 1214319-92-2 is a valid CAS Registry Number.
1214319-92-2Relevant articles and documents
DIRECTED CONJUGATION TECHNOLOGIES
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Paragraph 0581; 0582, (2021/05/29)
Among other things, the present disclosure provides technologies for site-directed conjugation of various moieties of interest to target agents. In some embodiments, the present disclosure utilizes target binding moieties to provide high conjugation efficiency and selectivity. In some embodiments, provided technologies are useful for preparing antibody conjugates.
