1215178-33-8Relevant articles and documents
Intra- and intermolecular alkylation of N, O-acetals and π-activated alcohols catalyzed by in situ generated acid
Hamon, Melanie,Dickinson, Niall,Devineau, Alice,Bolien, David,Tranchant, Marie-Jose,Taillier, Catherine,Jabin, Ivan,Harrowven, David C.,Whitby, Richard J.,Ganesan,Dalla, Vincent
, p. 1900 - 1912 (2014/04/03)
Intramolecular and intermolecular alkylations of carbocation precursors of limited ionization ability, principally N,O-acetals, without the use of an exogenous reagent have been developed. The reactions are carried out in 1,1,2,2-tetrachloroethane (TCE) a
N-acyliminium ion chemistry: Highly efficient and versatile carbon-carbon bond formation by nucleophilic substitution of hydroxy groups catalyzed by Sn(NTf2)4
Othman, Raja Ben,Affani, Radouane,Tranchant, Marie-Jose,Antoniotti, Sylvain,Dalla, Vincent,Dunach, Elisabet
supporting information; experimental part, p. 776 - 780 (2010/04/24)
(Chemical Equation Presentation) Atom-economical: Unmodified hemiN,O-acetals are used in a catalytic, highly efficient α- amidoalkylation of a broad range of carbon-centered nucleophiles, including silicon-based components, active methylene derivatives, electron-rich arenes, and even simple ketones (see scheme). The reactions proceed in a highly efficient manner and typically require only 1 mol% of the Lewis super-acidic reagent Sn(NTf2)4 as the catalyst.
