1215765-59-5

Basic information

• Product Name: tert-butyl 2-oxo-3-(phenylselanyl)piperidine-1-carboxylate
• Synonyms: tert-butyl 2-oxo-3-(phenylselanyl)piperidine-1-carboxylate
• CAS NO: 1215765-59-5
• Molecular Weight: 354.308
• Mol File: 1215765-59-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-butyl 2-oxo-3-(phenylselanyl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-oxo-3-(phenylselanyl)piperidine-1-carboxylate(1215765-59-5)
• EPA Substance Registry System: tert-butyl 2-oxo-3-(phenylselanyl)piperidine-1-carboxylate(1215765-59-5)

Safety Data

• Hazardous Substances Data: 1215765-59-5(Hazardous Substances Data)

Upstream product

• 5707-04-0 Phenylselenyl chloride 
• 85908-96-9 2-oxopiperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 128372-89-4 6-oxo-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 1361951-59-8 tert-butyl 2-oxo-4-(((3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-yl)amino)methyl)piperidine-1-carboxylate 
• 1361951-08-7 4-(((3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-yl)amino)methyl)piperidin-2-one 

Relevant articles and documents

Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors

The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.

Nitrogen ylide-mediated cyclopropanation of lactams and lactones

Cyclopropanation of α,β-unsaturated δ-lactams and δ-lactones mediated by nitrogen ylides is described. The process tolerates different alkyl halides and gives efficiently bicyclo[4.1.0]heptanes in a totally stereoselective manner. On the other hand, ε-lac