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121643-44-5

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121643-44-5 Usage

Description

2-Methoxy-3-(trifluoromethyl)pyridine is a pyridine derivative characterized by the presence of a methoxy group at the 2nd position and a trifluoromethyl group at the 3rd position on the pyridine ring. 2-Methoxy-3-(trifluoromethyl)pyridine is known for its potential applications in the pharmaceutical industry due to its unique chemical structure and properties.

Uses

Used in Pharmaceutical Industry:
2-Methoxy-3-(trifluoromethyl)pyridine is used as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its unique chemical structure allows it to serve as a building block in the development of new pharmaceutical compounds with potential therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-Methoxy-3-(trifluoromethyl)pyridine is utilized as a key component in the design and synthesis of novel drug candidates. Its presence in a molecule can influence the pharmacokinetic and pharmacodynamic properties of the drug, making it a valuable tool in the development of new therapeutic agents.
Used in Chemical Research:
2-Methoxy-3-(trifluoromethyl)pyridine is also employed in chemical research as a model compound to study the reactivity and properties of pyridine derivatives. This helps researchers understand the behavior of similar compounds and develop new synthetic strategies for the preparation of complex molecules with potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.

storage

2-Methoxy-3-(trifluoromethyl)pyridine store at room temperature.

Check Digit Verification of cas no

The CAS Registry Mumber 121643-44-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,6,4 and 3 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 121643-44:
(8*1)+(7*2)+(6*1)+(5*6)+(4*4)+(3*3)+(2*4)+(1*4)=95
95 % 10 = 5
So 121643-44-5 is a valid CAS Registry Number.

121643-44-5 Well-known Company Product Price

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  • TCI America

  • (M2191)  2-Methoxy-3-(trifluoromethyl)pyridine  >98.0%(GC)

  • 121643-44-5

  • 1g

  • 330.00CNY

  • Detail
  • TCI America

  • (M2191)  2-Methoxy-3-(trifluoromethyl)pyridine  >98.0%(GC)

  • 121643-44-5

  • 5g

  • 1,140.00CNY

  • Detail
  • Alfa Aesar

  • (B20599)  2-Methoxy-3-(trifluoromethyl)pyridine, 97%   

  • 121643-44-5

  • 2.5g

  • 564.0CNY

  • Detail
  • Alfa Aesar

  • (B20599)  2-Methoxy-3-(trifluoromethyl)pyridine, 97%   

  • 121643-44-5

  • 10g

  • 1803.0CNY

  • Detail
  • Aldrich

  • (658359)  2-Methoxy-3-(trifluoromethyl)pyridine  96%

  • 121643-44-5

  • 658359-1G

  • 442.26CNY

  • Detail
  • Aldrich

  • (658359)  2-Methoxy-3-(trifluoromethyl)pyridine  96%

  • 121643-44-5

  • 658359-5G

  • 1,633.32CNY

  • Detail

121643-44-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methoxy-3-(trifluoromethyl)pyridine

1.2 Other means of identification

Product number -
Other names 2-Methoxy-3-(trifluoroMethyl)pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:121643-44-5 SDS

121643-44-5Relevant articles and documents

Copper-mediated trifluoromethylation of aryl-, heteroaryl-, and vinyltrifluoroborates with Langlois' reagent

Dubbaka, Srinivas Reddy,Salla, Manohar,Bolisetti, Raghu,Nizalapur, Shashidhar

, p. 6496 - 6499 (2014)

An effortless and realistic procedure for the copper-mediated trifluoromethylation of aryl-, heteroaryl- and vinyltrifluoroborates with CF3 radicals generated from NaSO2CF3 and tert-butyl hydroperoxide (TBHP) is presented. The developed method produces trifluoromethyl arenes and -alkenes in good to excellent yields and a wide range of electronically and structurally diverse substrates are tolerated.

Metal- and oxidant-free photoinduced aromatic trifluoromethylation performed in aerated gel media: Determining the effects on yield and selectivity

Abramov, Alex,Vernickel, Hendrik,Saldías, César,Díaz, David Díaz

, (2019/01/14)

In this work we have investigated the potential benefits of using supramolecular gel networks as reaction media to carry out air-sensitive metal-free light-induced trifluoromethylation of six-membered (hetero)arenes under aerobic conditions. This reaction was performed at room temperature (RT) using sodium triflinate (CF3SO2Na, Langlois' reagent) as a source of radicals and diacetyl as electron donor. The effects of confinement in gel media, concentration of reactants, and type of light source on yield and product distribution were evaluated and compared to the results obtained in homogeneous solution. Four different low molecular weight (LMW) gelators were employed in this study. The results confirmed the blocking effect of the gel medium against reaction quenching by external oxygen, as well as a certain control on the kinetics and selectivity.

Use of Inhibitors of the Activity or Function of PI3K

-

Paragraph 0841-0842, (2016/01/09)

The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.

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