121668-46-0

Basic information

• Product Name: 2-(benzofuran-2-yl)benzoic acid
• Synonyms: 2-(benzofuran-2-yl)benzoic acid
• CAS NO: 121668-46-0
• Molecular Weight: 238.243
• Mol File: 121668-46-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-(benzofuran-2-yl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzofuran-2-yl)benzoic acid(121668-46-0)
• EPA Substance Registry System: 2-(benzofuran-2-yl)benzoic acid(121668-46-0)

Safety Data

• Hazardous Substances Data: 121668-46-0(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 129503-26-0 2-(2-Bromophenyl)[1]benzofuran 
• 6091-64-1 2-bromobenzoic acid ethyl ester 
• 271-89-6 1-benzofurane 
• 65-85-0 benzoic acid 
• 7154-66-7 2-bromobenzoic acid chloride 
• 129503-22-6 2-(2-methoxycarbonylbenzoyloxy)benzyltriphenylphosphonium bromide 
• 129503-23-7 {2-[(2-Bromobenzoyl)oxy]benzyl}triphenylphosphonium bromide 
• 70340-04-4 (2-hydroxybenzyl)triphenylphosphonium bromide 
• 4397-55-1 phthalic monoacid monomethyl ester chloride 
• 98437-24-2 benzofuran-2-boronic acid 
• 609-67-6 2-Iodobenzoyl chloride 
• 164226-49-7 ethyl 5-oxo-5H,6aH-benzofuro<3,2-c><2>benzopyran-11a-carboxylate 
• 69976-43-8 2-(2-(methoxycarbonyl)phenyl)benzo[b]furan 

Downstream Products

• 121668-45-9 2-(2-benzofuranyl)-benzamide 
• 867203-07-4 (2-(benzofuran-2-yl)phenyl)methanol 

Relevant articles and documents

A colored dendrimer as a new soluble support in organic synthesis. Part 1: Suzuki reaction

A new strategy using a colored dendrimer as visible soluble support for organic synthesis has been developed. The efficiency of this new system has been demonstrated by the use of DRHMPA9-CH2OH as the support in a Suzuki coupling reaction. Due to the visibility of the support, following of the reaction has been rendered easier and the purification time of the crude product has been considerably shortened.

C-H/C-H rhodium catalysis -based high-efficiency oxidation coupling reaction of preparing double-hetero aromatic ring and pyronone/cyclopentanone derivatives method

The invention relates to a method for efficiently preparing a di(hetero)arylbenzopyrone/cyclopentanone derivative through a rhodium catalysis-based C-H/C-H oxidation coupling reaction. The method comprises the following steps: 1, carrying out direct cross coupling on the C-H bond at the ortho position of the carboxyl group of a raw material (hetero)aryl carboxylic acid derivative and the C-H bond of a heteroarene derivative under the catalysis of rhodium to obtain an intermediate (orthoheteroaryl(hetero) aryl carboxylic acid derivative); and 2, carrying out an intramolecular acylation or esterification reaction to obtain the (hetero) arylbenzopyrone/cyclopentanone derivative. Compared with traditional methods, the preparation method provided by the invention has the advantages of concise synthesis steps, mild conditions, high synthesis yield, and cheap and easily available raw materials.

Synthetic Routes to 2-(2-Benzofuranyl)benzoic Acids and their Cyclization into Benzindenofuran-10-ones

The benzindenofuran-10-ones 1 were prepared by the intramolecular cyclization of the 2-(2-benzofuranyl)benzoic acids, 2, the unequivocal routes to which are described herein.Various synthetic methods to these acids were tested, as well as the methods to cyclize them.