1217625-62-1
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Basic information
- Product Name: COLCHICINE-D3
- Synonyms: COLCHICINE-D3;Colchineos-d3;Colchisol-d3;Colcin-d3;Colsaloid-d3;Condylon-d3;N-[(7S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide-d3;NSC 757-d3
- CAS NO:1217625-62-1
- Molecular Formula: C22H22D3NO6
- Molecular Weight: 402.46
- EINECS: N/A
- Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Isotope Labeled Compounds;Pharmaceuticals;Chiral Reagents;Isotope Labelled Compounds
- Mol File: 1217625-62-1.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: -20?C Freezer
- Solubility: N/A
- CAS DataBase Reference: COLCHICINE-D3(CAS DataBase Reference)
- NIST Chemistry Reference: COLCHICINE-D3(1217625-62-1)
- EPA Substance Registry System: COLCHICINE-D3(1217625-62-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1217625-62-1(Hazardous Substances Data)
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1217625-62-1 Usage
Description
COLCHICINE-D3 is an isotopically labeled antimitotic agent that disrupts microtubules by binding to tubulin and preventing its polymerization. It stimulates the intrinsic GTPase activity of tubulin and induces apoptosis in several normal and tumor cell lines while activating the JNK/SAPK signaling pathway. COLCHICINE-D3 is a light-brown crystal.Uses
Used in Pharmaceutical Industry:COLCHICINE-D3 is used as an antimitotic agent for its ability to disrupt microtubules and induce apoptosis in normal and tumor cell lines. Its activation of the JNK/SAPK signaling pathway makes it a potential candidate for cancer treatment and research.
Used in Research Applications:
COLCHICINE-D3 is used as a research tool for studying the effects of microtubule disruption and tubulin polymerization inhibition on cell cycle regulation and apoptosis induction. Its ability to stimulate the intrinsic GTPase activity of tubulin makes it valuable for investigating the underlying mechanisms of these processes.
Check Digit Verification of cas no
The CAS Registry Mumber 1217625-62-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,7,6,2 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.Calculate Digit Verification of CAS Registry Number 1217625-62:
(9*1)+(8*2)+(7*1)+(6*7)+(5*6)+(4*2)+(3*5)+(2*6)+(1*2)=141
141 % 10 = 1
So 1217625-62-1 is a valid CAS Registry Number.
1217625-62-1Upstream product
1217625-62-1Downstream Products
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COLCHICINE-D3
