121821-01-0

Basic information

• Product Name: 2-(3-AMINOPROPYL)-1H-ISOINDOLE-1,3(2H)-DIONE, HCL SALT
• Synonyms: N-(3-AMINO-PROPYL)-PHTHALIMIDE HYDROCHLORIDE;2-(3-AMINOPROPYL)-1H-ISOINDOLE-1,3(2H)-DIONE, HCL SALT;2-(3-Aminopropyl)-1H-isoindole-1,3(2H)-dionehydrochloride;2-(3-aMinopropyl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride;1H-Isoindole-1,3(2H)-dione, 2-(3-aMinopropyl)-, hydrochloride;2-(3-Aminopropyl)isoindole-1,3(2H)-dione hydrochloride
• CAS NO: 121821-01-0
• Molecular Formula: C₁₁H₁₂N₂O₂*ClH
• Molecular Weight: 240.69
• Mol File: 121821-01-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2-(3-AMINOPROPYL)-1H-ISOINDOLE-1,3(2H)-DIONE, HCL SALT(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-AMINOPROPYL)-1H-ISOINDOLE-1,3(2H)-DIONE, HCL SALT(121821-01-0)
• EPA Substance Registry System: 2-(3-AMINOPROPYL)-1H-ISOINDOLE-1,3(2H)-DIONE, HCL SALT(121821-01-0)

Safety Data

• Hazardous Substances Data: 121821-01-0(Hazardous Substances Data)

Usage

General Description

2-(3-aminopropyl)-1H-isoindole-1,3(2H)-dione, HCl salt is a chemical compound that is a salt form of the isoindole derivative. It is often used in research settings as a building block for the synthesis of various bioactive compounds. Its structure contains an isoindole-1,3-dione core with a 3-aminopropyl side chain, and the HCl salt form is often used to enhance the compound's solubility in aqueous solutions. 2-(3-AMINOPROPYL)-1H-ISOINDOLE-1,3(2H)-DIONE, HCL SALT may have potential applications in medicinal chemistry, particularly for the development of new pharmaceuticals targeting a range of biological processes. However, it is important to handle and use this chemical with appropriate safety precautions due to its potential hazards.

Upstream product

• 22641-00-5 2,3,4,5-tetrahydroisoindolino<2,1-a>pyrimidin-6-one 
• 10513-96-9 1,3-diphthalimidopropane 

Downstream Products

• 38353-77-4 N-(N³-p-toluenesulfonyl)-3-aminopropylphthalimide 
• 121821-32-7 4,9,13,18-tetratosyl-N¹,N¹:N²¹,N²¹-diphthaloyl-4,9,13,18-tetraazaheneicosane-1,21-diamine 
• 121821-31-6 N,N'-bis(3-phthalimidopropyl)-N,N'-ditosyl-1,3-propanediamine 
• 121821-26-9 4,8,13,17-tetratosyl-N¹,N¹:N²⁰,N²⁰-diphthaloyl-4,8,13,17-tetraazaeicosane-1,20-diamine 
• 107976-61-4 N,N'-bis(3-phthalimidopropyl)-N,N'-ditosyl-1,4-butanediamine 
• 88597-05-1 N-<3-(N-nitroso-p-tolylsulfonamido)propyl>phthalimide 
• 88597-06-2 3-(phthalimido)propyl-p-toluenesulfonate 
• 56642-94-5 N¹,N¹:N⁷,N⁷-diphthaloyl-4-tosyl-4-azaheptane-1,7-diamine 

Relevant articles and documents

Design and Synthesis of Macromonocyclic Polyamines Composed of Natural Methylene Arrays

A general synthetic method applicable to acyclic and cyclic polyamines was developed.The methodology was exemplified by systematical synthesis of twelve macromonocyclic polyamines, 1 (N4) through 12 (N8), composed of the combination of four natural polyamine segments, spermidine, spermine, thermine, and thermospermine.These twelve designed macrocycles are exhausted numbers of possible structures defined by three arbitrarily chosen criteria concerning with methylene chain arrays and nitrogen content (four to eight).The common elements of the structural characteristics were analyzed and were found to be reduced to readily available three classes of simple N,N'-ditosylalkanediamines derived from diamines and triamine.Nitrogen content was increased systematically through the reaction of N,N'-ditosylalkanediamine with one of three ω-phthalimidated electrophiles followed by regeneration of the same functionality at symmetrical both terminals as the starting materials via a series of transformation reaction, in excellent yields.Tractable formamide intermediate profits the facile synthesis of acyclic polyamines with long chains.Cyclization was achieved, under high dilution conditions, through the reaction of α,ω-bis(tosylamide) with α,ω-ditosylates in DMF in the presence of cesium carbonate.The cyclization occurred in practical synthetic yields even in the formation of multi-membered ring when the shorter electrophile and the longest α,ω-bis(tosylamide) reacted.