1218791-07-1 Usage
Description
5-Formylfuran-2-boronic acid, neopentyl glycol ester is an organic compound that serves as a valuable reagent in the synthesis of various pharmaceutical compounds. It is characterized by its unique chemical structure, which includes a formyl group, a furan ring, and a boronic acid functional group, as well as an ester linkage with neopentyl glycol. This combination of functional groups allows for versatile applications in the field of medicinal chemistry.
Uses
Used in Pharmaceutical Synthesis:
5-Formylfuran-2-boronic acid, neopentyl glycol ester is used as a synthetic reagent for the production of lapatinib, a tyrosine kinase inhibitor used in the treatment of certain types of cancer. Its unique chemical structure enables the formation of complex molecular frameworks, making it a valuable tool in the development of novel therapeutic agents.
In the synthesis of lapatinib, the 5-formylfuran-2-boronic acid, neopentyl glycol ester serves as a key intermediate, facilitating the formation of the desired molecular structure through a series of chemical reactions. Its boronic acid functionality allows for selective coupling reactions, while the formyl group and furan ring provide additional points of reactivity and structural diversity.
Overall, 5-Formylfuran-2-boronic acid, neopentyl glycol ester is a versatile and valuable reagent in the field of pharmaceutical synthesis, particularly in the development of novel cancer treatments. Its unique chemical structure and reactivity make it an essential component in the synthesis of lapatinib and other potential therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1218791-07-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,8,7,9 and 1 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1218791-07:
(9*1)+(8*2)+(7*1)+(6*8)+(5*7)+(4*9)+(3*1)+(2*0)+(1*7)=161
161 % 10 = 1
So 1218791-07-1 is a valid CAS Registry Number.
1218791-07-1Relevant articles and documents
Aerobic Visible-Light-Driven Borylation of Heteroarenes in a Gel Nanoreactor
Herrera-Luna, Jorge C.,Diaz Diaz, David,Abramov, Alex,Encinas, Susana,Jimenez, M. Consuelo,Perez-Ruiz, Raul
supporting information, p. 2320 - 2325 (2021/04/05)
Heteroarene boronate esters constitute valuable intermediates in modern organic synthesis. As building blocks, they can be further applied to the synthesis of new materials, since they can be easily transformed into any other functional group. Efforts toward novel and efficient strategies for their preparation are clearly desirable. Here, we have achieved the borylation of commercially available heteroarene halides under very mild conditions in an easy-to-use gel nanoreactor. Its use of visible light as the energy source at room temperature in photocatalyst-free and aerobic conditions makes this protocol very attractive. The gel network provides an adequate stabilizing microenvironment to support wide substrate scope, including furan, thiophene, selenophene, and pyrrole boronate esters.
