1218805-88-9

Basic information

• Product Name: N-(2,2-dimethylpropyl)-2-[7-(3-fluorophenyl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]acetamide
• CAS NO: 1218805-88-9
• Molecular Weight: 357.428
• Mol File: 1218805-88-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2,2-dimethylpropyl)-2-[7-(3-fluorophenyl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,2-dimethylpropyl)-2-[7-(3-fluorophenyl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]acetamide(1218805-88-9)
• EPA Substance Registry System: N-(2,2-dimethylpropyl)-2-[7-(3-fluorophenyl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]acetamide(1218805-88-9)

Safety Data

• Hazardous Substances Data: 1218805-88-9(Hazardous Substances Data)

Upstream product

• 1218810-48-0 ethyl (7-iodo-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl)acetate 
• 1218810-47-9 ethyl (2E)-4-{[(4-iodo-1H-pyrrol-2-yl)carbonyl]amino}but-2-enoate 

Downstream Products

• 1429925-20-1 N-[(1S)-1-cyclohexyl-2-(4-methylpiperazin-1-yl)ethyl]-2-[(4S)-7-(2-fluoropyridin-4-yl)-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]acetamide 

Relevant articles and documents

Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases

A novel series of PIM inhibitors was derived from a combined effort in natural product-inspired library generation and screening. The novel pyrrolo[1,2-a]pyrazinones initial hits are inhibitors of PIM isoforms with IC50 values in the low microm