122033-54-9

Basic information

• Product Name: 4-BROMO-2,3,5,6-TETRAFLUOROBENZOYL CHLORIDE
• Synonyms: 4-BROMO-2,3,5,6-TETRAFLUOROBENZOYL CHLORIDE;B169
• CAS NO: 122033-54-9
• Molecular Formula: C₇BrClF₄O
• Molecular Weight: 291.42
• EINECS: -0
• Mol File: 122033-54-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 95-100°C
• Flash Point: 95-100°C
• Appearance: /
• Density: 1.957 g/cm³
• Vapor Pressure: 0.139mmHg at 25°C
• Refractive Index: 1.5170
• Sensitive: Moisture Sensitive
• BRN: 7295811
• CAS DataBase Reference: 4-BROMO-2,3,5,6-TETRAFLUOROBENZOYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2,3,5,6-TETRAFLUOROBENZOYL CHLORIDE(122033-54-9)
• EPA Substance Registry System: 4-BROMO-2,3,5,6-TETRAFLUOROBENZOYL CHLORIDE(122033-54-9)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: 3265
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 122033-54-9(Hazardous Substances Data)

Usage

General Description

4-Bromo-2,3,5,6-Tetrafluorobenzoyl chloride is a multifunctional and complex chemical compound. It is extensively used in the field of synthetic chemistry. 4-BROMO-2,3,5,6-TETRAFLUOROBENZOYL CHLORIDE is characterized by the presence of several halogens in its molecular structure, including bromine (Br), fluorine (F), and chlorine (Cl), along with carbon (C) and hydrogen (H). The presence of these halogens makes this compound highly reactive, and its functionality varies based on the type of reaction it undergoes. It is often used as a reagent, a substance that is used in chemical reactions to detect, measure, examine, or produce other substances. Care needs to be taken while handling this chemical due to its reactive nature.

InChI:InChI=1/C7BrClF4O/c8-2-5(12)3(10)1(7(9)14)4(11)6(2)13

Upstream product

• 4707-24-8 4-bromotetrafluorobenzenecarboxylic acid 

Downstream Products

• 1260097-17-3 2,9-bis(4-bromo-2,3,5,6-tetrafluoro-phenyl)-1,3,8,10-tetraazaperopyrene 
• 122033-55-0 3-(4-Bromo-2,3,5,6-tetrafluoro-phenyl)-3-oxo-propionic acid ethyl ester 
• 123942-19-8 ethyl 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-6-fluoro-4-oxo-5-<(phenylmethyl)thio>-3-quinolinecarboxylate 
• 123942-22-3 ethyl 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-6-fluoro-4-oxo-5-(phenylthio)-3-quinolinecarboxylate 
• 123942-18-7 (Z)-2-(4-Bromo-2,3,5,6-tetrafluoro-benzoyl)-3-cyclopropylamino-acrylic acid ethyl ester 
• 123942-17-6 (Z)-2-(4-Bromo-2,3,5,6-tetrafluoro-benzoyl)-3-dimethylamino-acrylic acid ethyl ester 
• 123942-05-2 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid 

Relevant articles and documents

Concurring Chalcogen- and Halogen-Bonding Interactions in Supramolecular Polymers for Crystal Engineering Applications

The engineering of crystalline molecular solids through the simultaneous combination of distinctive non-covalent interactions is an important field of research, as it could allow chemist to prepare materials depicting multi-responsive properties. It is in this context that, pushed by a will to expand the chemical space of chalcogen-bonding interactions, a concept is put forward for which chalcogen- and halogen-bonding interactions can be used simultaneously to engineer multicomponent co-crystals. Through the rational design of crystallizable molecules, chalcogenazolo pyridine scaffold (CGP) modules were prepared that, bearing either a halogen-bond acceptor or donor at the 2-position, can interact with suitable complementary molecular modules undergoing formation of supramolecular polymers at the solid state. The recognition reliability of the CGP moiety to form chalcogen-bonded dimers allows the formation of heteromolecular supramolecular polymers through halogen-bonding interactions, as confirmed by single-crystal X-ray diffraction analysis.

Pyridinyl-quinolone compounds, their preparation and use

Fluorinated 1-cyclopropyl-7-(substituted-pyridinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids of the formula STR1 wherein R is hydrogen, R' and R" are hydrogen or fluoro, or other groups and Z is 3- or 4-pyridinyl substituted by alkyl groups or substituted alkyl groups, are superior antibacterial agents. They are prepared via a coupling reaction between the corresponding esters (R=alkyl) having a halo group in the 7-position and a substituted (trialkylstannyl)pyridine.