1220716-00-6

Basic information

• Product Name: C₂₆H₃₄BNO₅
• CAS NO: 1220716-00-6
• Molecular Weight: 451.371
• Mol File: 1220716-00-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₄BNO₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₄BNO₅(1220716-00-6)
• EPA Substance Registry System: C₂₆H₃₄BNO₅(1220716-00-6)

Safety Data

• Hazardous Substances Data: 1220716-00-6(Hazardous Substances Data)

Upstream product

• 760990-10-1 2-amino-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenol 
• 1878-56-4 2-(4-cyclohexylphenoxy)acetic acid 

Downstream Products

• 1220716-05-1 C₂₀H₂₄BNO₅ 

Relevant articles and documents

Boron-containing phenoxyacetanilide derivatives as hypoxia-inducible factor (HIF)-1α inhibitors

A series of boron-containing phenoxyacetanilide derivatives 8a-f, 9a-f, 15, and 16 were synthesized as hypoxia-inducible factor (HIF)-1α inhibitors. Among the compounds synthesized, carboranylphenoxyacetanilide 16 (GN26361) was found to be a potent inhibitor against HIF-1α accumulation under hypoxic conditions and inhibited the hypoxia-induced HIF-1 transcriptional activity in HeLa cells (IC50 = 0.74 μM). Compound 16 suppressed hypoxia-induced HIF-1α accumulation and vascular endothelial growth factor mRNA expression in a concentration-dependent manner without affecting the expression of HIF-1α mRNA.