1221171-81-8 Usage
Description
3-(trifluoroMethoxy)picolinic acid is a chemical compound with the molecular formula C7H5F3NO3, derived from pyridine and featuring a picolinic acid group with a trifluoromethoxy substituent. It is recognized for its potential anti-inflammatory and antitumor properties, and its trifluoromethoxy group enhances its utility in the development of new drugs, making it a versatile building block in pharmaceutical and agrochemical research.
Uses
Used in Pharmaceutical Research:
3-(trifluoroMethoxy)picolinic acid is used as a building block for the synthesis of biologically active compounds due to its potential anti-inflammatory and antitumor properties, contributing to the development of new drugs in the pharmaceutical industry.
Used in Agrochemical Research:
In agrochemical research, 3-(trifluoroMethoxy)picolinic acid serves as a key component in the synthesis of compounds with pesticidal or herbicidal activity, leveraging its structural features to create effective agrochemicals.
Used in Coordination Chemistry Studies:
3-(trifluoroMethoxy)picolinic acid is used as a ligand for metal complexes, playing a crucial role in coordination chemistry studies where it helps in understanding the interactions between metal ions and organic ligands, potentially leading to advances in materials science and catalysis.
Overall, 3-(trifluoroMethoxy)picolinic acid's diverse applications in medicinal chemistry and chemical biology underscore its importance in the synthesis and study of compounds with significant biological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 1221171-81-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,1,1,7 and 1 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1221171-81:
(9*1)+(8*2)+(7*2)+(6*1)+(5*1)+(4*7)+(3*1)+(2*8)+(1*1)=98
98 % 10 = 8
So 1221171-81-8 is a valid CAS Registry Number.
1221171-81-8Relevant articles and documents
A general approach to (trifluoromethoxy)pyridines: First X-ray structure determinations and quantum chemistry studies
Manteau, Baptiste,Genix, Pierre,Brelot, Lydia,Vors, Jean-Pierre,Pazenok, Sergiy,Giornal, Florence,Leuenberger, Charlotte,Leroux, Frederic R.
experimental part, p. 6043 - 6066 (2011/02/26)
The previously unknown 2-, 3-, and 4-(trifluoromethoxy)pyridines have now become readily accessible by means of an efficient and straightforward large-scale synthesis. Their regioselective functionalization by organometallic methods has been studied and has afforded new and highly important building blocks for life-sciences-oriented research. In addition, the first X-ray crystallographic structure determinations of (trifluoromethoxy)pyridines have been performed. Lowest-energy conformations of (trifluoromethoxy)pyridines and (trifluoromethoxy)pyridinium cations were determined by in silico studies. A general and efficient route to (trifluoromethoxy)pyridines is reported. Regioselective functionalization by organometallic methods afforded new and highly important building blocks for life-sciences-oriented research. The first X-ray crystallographic structure determinations of (trifluoromethoxy)pyridines have been performed and supported by in silico studies.
